#Methamphetamine vs amphetamine series#
#Methamphetamine vs amphetamine free#

In the 1950s, there was a rise in the legal prescription of methamphetamine to the American public. ĭuring World War II, both the Allied and Axis forces experimented giving amphetamine and methamphetamine to select servicemen for their stimulant and performance-enhancing effects. The two most commonly reported drug effects were 'a sense of well being and a feeling of exhilaration' and 'lessened fatigue in reaction to work'. He studied the subjective effects of amphetamine in 55 hospital workers who were each given 20 mg of Benzedrine.

Nathanson, a Los Angeles physician, in 1935. One of the first attempts at using amphetamine in a scientific study was done by M.

#Methamphetamine vs amphetamine free#

In 1934, Smith, Kline & French made the first amphetamine pharmaceutical when they began selling a decongestant inhaler containing the volatile amphetamine free base under the trade name Benzedrine. At the time, Alles referred to the amphetamine compound as Benzedrine, a term derived from the name benzyl-methyl carbinamine. The sympathomimetic properties of amphetamine were unknown until 1927, when pioneer psychopharmacologist Gordon Alles independently resynthesized it and tested it on himself while searching for an artificial replacement for ephedrine. In 1919, methamphetamine hydrochloride, also known as crystal meth, was synthesized by pharmacologist Akira Ogata via reduction of ephedrine using red phosphorus and iodine. Shortly after the first synthesis of amphetamine, Nagai synthesized methamphetamine from ephedrine in 1893.

#Methamphetamine vs amphetamine series#

This concoction was one of a series of compounds related to the plant derivative ephedrine, which had been isolated from the Chinese ephedra plant that same year by Nagai Nagayoshi. Obetrol, a pharmaceutical mixture of amphetamine and methamphetamine salts, was medically indicated and marketed for treating obesity, as illustrated in this advertisement from 1970.Īmphetamine was first synthesized in 1887 in Germany by Romanian chemist, Lazăr Edeleanu, who named the drug phenylisopropylamine.

Based on seizures of drugs and precursor chemicals, illicit amphetamine production and trafficking is much less prevalent than that of methamphetamine. ĭue to the large underground market for these drugs, they are often illegally synthesized by clandestine chemists, trafficked, and sold on the black market. Despite strict government controls, amphetamine and methamphetamine have been used (legally or illegally) by individuals from a variety of backgrounds for a variety of purposes.

During the early 1970s in the United States, amphetamine was initially classified as a schedule III controlled substance under the Controlled Substances Act, but then became a schedule II controlled substance under the Psychotropic Substances Act. As the addictive properties of the drugs became known, governments began to place strict controls on the sale of the drugs. ĭuring World War II, amphetamine and methamphetamine were used extensively by Allied and Axis forces for their stimulant and performance-enhancing effects. Neither drug had a pharmacological use until 1934, when Smith, Kline & French began selling amphetamine as an inhaler under the trade name Benzedrine for congestion. Methamphetamine was synthesized from ephedrine in 1893 by Nagayoshi. Around the same time, Japanese organic chemist Nagai Nagayoshi isolated ephedrine from the Chinese ephedra plant and later developed a method for ephedrine synthesis. When used recreationally, they are colloquially known as 'speed.' Amphetamine was first synthesized in 1887 in Germany by Romanian chemist Lazăr Edeleanu, who named it phenylisopropylamine. This article is about the socio-cultural aspects and history of amphetamine and methamphetamine.Īmphetamine and methamphetamine are central nervous system stimulants used to treat a variety of conditions.